Can Machine Learning Guide Directed Evolution of Functional Proteins
نویسندگان
چکیده
منابع مشابه
How Learning Can Guide Evolution
The assumption that acquired characteristics are not inherited is often taken to imply that the adaptations that an organism learns during its lifetime cannot guide the course of evolution. This inference is incorrect (Baldwin, 1896). Learning alters the shape of the search space in which evolution operates and thereby provides good evolutionary paths towards sets of co-adapted alleles. We demo...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2020
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2019.11.1888